PNU-177864 hydrochloride
CAS No. 1783978-03-9
PNU-177864 hydrochloride ( PNU-177864 (hydrochloride) )
产品货号. M26387 CAS No. 1783978-03-9
PNU-177864 hydrochloride is a selective antagonist of D3 receptor with antischizophrenic activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥405 | 有现货 |
|
10MG | ¥608 | 有现货 |
|
25MG | ¥1037 | 有现货 |
|
50MG | ¥1555 | 有现货 |
|
100MG | ¥2325 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称PNU-177864 hydrochloride
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述PNU-177864 hydrochloride is a selective antagonist of D3 receptor with antischizophrenic activity.
-
产品描述PNU-177864 hydrochloride is a selective antagonist of D3 receptor with antischizophrenic activity.(In Vivo):In Sprague-Dawley rats, PNU-177864 hydrochloride (8-200 mg/kg; gavage) induces phospholipidosis in unusual target organs including epididymis, hair follicles and pituitary.
-
同义词PNU-177864 (hydrochloride)
-
通路GPCR/G Protein
-
靶点Dopamine Receptor
-
受体VHL
-
研究领域——
-
适应症——
化学信息
-
CAS Number1783978-03-9
-
分子量438.9
-
分子式C18H22ClF3N2O3S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCl.O=S(=O)(NC1=CC=C(C=C1)CCNCCC)C2=CC=C(OC(F)(F)F)C=C2
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
产品手册
关联产品
-
A 77636 hydrochlorid...
A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).
-
Rotigotine hydrochlo...
A non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM); has 10-fold selectivity for the D3 receptor over the D2, D4, and D5 receptors and 100-fold selectivity for the D3 receptor over the D1 receptor.
-
L-745870 trihydrochl...
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. L-745870 trihydrochloride exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors and shows weaker affinity for D2 and D3 receptors.